Risk Factors And Prognostic Impact of Sleep Alterations in Icu Patients - a Prospective Observational Polysomnographic Study

Objectives The aims of our study were: 1) to identify risk factors of sleep abnormalities in non-sedated ICU patients 2) to describe the consequences of sleep disturbances on the outcome. Patients and Methods This is an ancillary study of a single center randomized controlled trial. Inclusion criteria were: 1) no sedation for >24h, 2) sedation level < 3 on the Ramsay scale, 3) expected remaining ICU stay >48 hours, 4) morphine < 0.01 mg/kg/min, 5) norepinephrine < 0.3μg/Kg/min. A 17h polysomnography was performed on the day of inclusion. Patients completed the Hospital and Anxiety depression scale at ICU and hospital discharge and at Day-90.